Vibrant Emotional Health

Exploring the dynamics of Psyche 2.0 reveals familiar relational patterns emerging in a new context. In this six-layer encounter, past relational dynamics are projected onto AI, similar to how patients in analytic therapy transfer past experiences onto their therapists. This transferential dynamic, while pseudo-interpersonal, is functionally real. As individuals track their responses to the AI system and the reciprocal influences at play, they could engage in a discipline reminiscent of countertransference in analysis as a way to manage the distorting forces. In relational psychoanalytic terms, the moments when human and AI interactions yield unintended dynamics—such as AI hallucinations or users becoming immersed in self-reinforcing fantasies—are referred to as enactments. Dissociation can also play a significant role, particularly in deeper cases where individuals may find themselves drawn into an AI-generated realm of fantasy and illusion. This experience can dissipate unexpectedly, leading to troubling real-world consequences. For further insights, you can read more at the provided link. #artificialintelligence #neuroscience #consciousness #psychoanalysis #AIHallucination

The Clinical Neuroscience Singularity is arriving. Research methodology and long years of dedicated, meticulous work reveal fine-grained mechanisms for brain stimulation. AI approaches based on foundational work over the years, and the rich training data thereby available, are very likely to lead to new major discoveries very soon. Precision neuromodation in clinical practice is already a reality, and will only improve. Props to the UCLA team — Gongwer, DeNardo, Wilke, Leuchter and colleagues — on this landmark Cell paper. This is the kind of mechanistic work the TMS field has needed for years. Using a clinically faithful rodent model of accelerated intermittent theta-burst stimulation (aiTBS), they show the antidepressant effect works through a specific cell type: intratelencephalic (IT) projection neurons in dorsomedial PFC. The pyramidal tract (PT) neurons sitting right next to them are largely untouched. Key findings: IT neurons show persistent, cumulative activation across an aiTBS session aiTBS restores stress-induced dendritic spine loss on IT neurons only Chemogenetically silencing IT neurons during stimulation abolishes the antidepressant effect; silencing PT neurons does not Behavioral and structural effects persist at least a week from a single treatment day Why this matters clinically: in our practice, non-navigated accelerated TMS is getting >95% response rates (≥50% MADRS improvement) and ~70% remission for MDD, often with complex comorbidities (most typically undiagnosed post-traumatic and dissociative disorder in my experience, and more typically pre-identified OCD, anxiety and personality issues). This paper helps explain in a murine model why a relatively broad magnetic pulse can produce such precise therapeutic outcomes — the biology is selective even when the field is not. The cortex sorts the signal for us.

I often review cybersecurity job descriptions and just face palm and shake my head. 🧐🤨🤦♂️ So many JDs just don’t match the job title or role. For example, say a company is hiring for a Security Engineer in title, but then you read the JD & responsibilities and what they’re really asking for is a manager, or it’s 3-4 different jobs in 1. Or they’re hiring for a Security Manager, and what they really want/need is an Engineer, or a Director, or CISO. Or Analysts doing engineering work. Or worse…. they’re looking for the mythical purple squirrel 🐿️🦄. So many times I just wish I could message the company, recruiter, hiring manager and tell them their JD doesn’t match the role or make sense. It’s no wonder hiring is so messed up! Companies & hiring managers don’t know what they really need. And they don’t know what the jobs really are. And companies don’t want to spend the $$$ for multiple jobs that require different skills. Do better.